I know that this is quite old, but for some reason this happens to me in Outlook only.
Triggers are being invoked (shown in "Recently used"), but for some reason in Outlook it doesn't work, but for example in Beyond Compare same trigger is working (the actual BC shortcut is different compared to Outlook)
BC:
Outlook:
"Auto adapt to current keyboard layout." is activated for all triggers.
I'm not 100% if this was working before.
BTT Version: 5.155 (2025013107)