One of my Keyboard Shortcuts stopped working a week or so ago - possibly after a macOS Beta update. This shortcut used CTRL-OPT-CMD-[DELETE] as a trigger. When I opened BTT to see what was going on, I noticed that the "Click here to record a shortcut" field would not show an entry if I held those four keys down. However, other key combos still worked - e.g. SHIFT-OPT-CMD-[DELETE].
macOS 12.3 Beta (21E5196i)
MacBook Pro (15-inch, 2016)
BTT 3.741 (1883)
BetterTouchToolDebug.zip (295.5 KB)